-
Chapter 1: Levels of Gene Control
The evidence that eukaryotic gene expression must be a highly regulated process is available…
-
Chapter 2: Transcription in Bacteria
As discussed in Chapter 1, transcription and translation are integral components of genetic information…
-
Chapter 3: Gene Regulation in Bacteria
Gene regulation is a fundamental mechanism that allows for the variation in gene expression…
-
Chapter 4: Structure of Chromatin
In previous chapters, we discussed the evidence indicating that the primary control of gene…
-
Chapter 5: The Epigenome – The Role of Chromatin Structure in Gene Control
As discussed in Chapter 1, the processes that control gene expression during cellular differentiation…
-
Chapter 6: Transcription in Eukaryotes
As discussed in Chapter 1 (Section 1.5), a variety of evidence demonstrates that gene…
-
Chapter 7: Transcription Factors and Transcriptional Control
As discussed in Chapter 6, the expression of specific genes in particular cell types…
-
Chapter 8: Post-Transcriptional Processes
In both prokaryotes and eukaryotes, the transcription of DNA into RNA represents the first…
-
Chapter 9: Post-Transcriptional Regulation
The evidence discussed in Chapters 1–3 indicates that in living organisms at least the…
-
Chapter 10: Gene Control and Cellular Signaling Pathways
As described in Chapter 6, transcription factors are essential for the process of eukaryotic…
-
Chapter 11: Gene Control in Embryonic Development
One of the central problems of biological sciences is to understand the manner in…
-
Chapter 12: Control of Cell Type-Specific Gene Expression
As discussed in Chapter 11, the regulation of gene expression plays a key role…
-
Chapter 13: Gene Regulation and Cancer
As we have discussed in the preceding chapters, the regulation of gene expression in…
-
Chapter 14: Gene Regulation and Human Disease
The central role of gene control processes in normal cellular function which has been…
-
Chapter 15: Conclusions
The pioneering studies of Jacob and Monod on the Lac operon in the 1950s…